Antiphospholipid syndrome in patients over 65 years: A comparative study of clinical and biological features and thrombotic relapses.
Colombe MassonThi T An NguyenVirginie DufrostMarie AudrainCaroline HémontChristian AgardMathieu ArtifoniJérôme ConnaultMarc FouassierMohamed HamidouAlexis F GuedonDenis WahlStéphane ZuilyOlivier EspitiaPublished in: Lupus (2022)
In this study, APS was different in patients aged more than 65 years, with a male predominance and more myocardial infarctions and LLDVT at diagnosis. Single antiphopholipid positivity and aCL IgM were more frequent in older patients. Older patient with APS had more thrombotic recurrence during follow-up. Compared to elderly controls, elderly APS patients had more thrombosis recurrences and poorer survival.