Humoral Immune Response to Clostridioides difficile Toxins A and B in Hospitalized Immunocompromised Patients With C difficile Infection.

Carolyn D AlonsoKonstantinos PapamichaelRebecca Sprague Caitlin Barrett Anne J Gonzales-Luna Kaitlyn Daugherty Kevin W Garey Javier A Villafuerte GálvezHua XuQianyun LinLamei WangXinhua ChenNira R Pollock Ciarán P Kelly

Published in: Open forum infectious diseases (2021)

The ICHs with CDI demonstrated lower levels of C difficile antitoxin antibodies in serum and stool during early CDI therapy compared with non-ICHs. These data provide insight into the humoral response to CDI in ICHs.

Keyphrases

immune response
clostridium difficile
dendritic cells
toll like receptor
electronic health record
big data
mesenchymal stem cells
machine learning
deep learning
intensive care unit
data analysis
extracorporeal membrane oxygenation