Two sensitizing oxidation products of p-phenylenediamine patch tested in patients allergic to p-phenylenediamine.
Ewa YoungErik ZimersonMagnus BruzeCecilia SvedmanPublished in: Contact dermatitis (2015)
The results show that 4-nitroaniline and 4,4'-azodianiline, formed during oxidation of PPD, are potent sensitizers. PPD-sensitized patients react to a high extent to concentrations equimolar to PPD of 4-nitroaniline and 4,4'-azodianiline.