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Prognostic Significance of Pathologic Lymph Node Invasion in Metastatic Renal Cell Carcinoma in the Immunotherapy Era.

Lukas ScheipnerFrancesco BarlettaCristina Cano GarciaReha-Baris IncesuSimone MorraAndrea BaudoAnis AssadZhe TianFred SaadShahrokh F ShariatAlberto BrigantiFelix K H ChunDerya TilkiNicola LongoLuca CarmignaniMartin PichlerSascha AhyaiPierre I Karakiewicz
Published in: Annals of surgical oncology (2023)
Pathologically confirmed lymph node invasion independently predicted higher CSM and OM for surgically treated mRCC patients. For pN1 mRCC patients, use of postoperative systemic therapy was associated with lower CSM and OM. Consequently, N stage should be considered for individual patient counseling and clinical decision-making. Consort diagram of the study population.
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