HLA Associations of Intrathecal IgG Production against Specific Viruses in Multiple Sclerosis.

Stephan NeidhartBenjamin VladMarc HiltyKlara Asplund HögelinMario ZieglerErnesto Berenjeno-CorreaIna ReichenPernilla StridhIvan JelcicMohsen KhademiIngrid KockumMireia SospedraFaiez Al NimerRoland MartinIlijas Jelcic

Published in: Annals of neurology (2024)

HLA-DRB1*15:01, the strongest genetic risk factor for MS, and female sex, 1 of the most prominent demographic risk factors for developing MS, predispose in MS/CIS patients for a positive MRZ reaction, the most specific CSF biomarker for MS. ANN NEUROL 2024.

Keyphrases

multiple sclerosis
mass spectrometry
ms ms
end stage renal disease
white matter
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
dna methylation
patient reported