Dl-3-n-Butylphthalide Alleviates Secondary Brain Damage and Improves Working Memory After Stroke in Cynomolgus Monkeys.
Zimu JiangJiating WeiJiahui LiangWeixian HuangFubing OuyangChunyong ChenPingping LiSuhan CaoYuangui CaiJianle LiBaozi HuangJinsheng ZengYicong ChenPublished in: Stroke (2024)
Our findings indicate that NBP improves working memory by alleviating remote secondary neurodegeneration and neuroinflammation in the ipsilateral dorsal lateral prefrontal cortex and thalamus after MCAO in cynomolgus monkeys.
Keyphrases
- working memory
- prefrontal cortex
- transcranial direct current stimulation
- attention deficit hyperactivity disorder
- spinal cord
- cerebral ischemia
- traumatic brain injury
- oxidative stress
- white matter
- lipopolysaccharide induced
- minimally invasive
- lps induced
- mouse model
- cognitive impairment
- blood brain barrier
- inflammatory response
- spinal cord injury
- brain injury
- subarachnoid hemorrhage