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828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser.

Marie KluftsAlejandro Martínez JiménezSimon LotzMuhammad Asim BashirTom PfeifferAlexander MlynekWolfgang WieserAlexander ChamorovskiyAdrian BraduAdrian PodoleanuRobert Huber
Published in: Biomedical optics express (2023)
This paper presents a Fourier domain mode locked (FDML) laser centered around 840 nm. It features a bidirectional sweep repetition rate of 828 kHz and a spectral bandwidth of 40 nm. An axial resolution of ∼9.9 µm in water and a 1.4 cm sensitivity roll-off are achieved. Utilizing a complex master-slave (CMS) recalibration method and due to a sufficiently high sensitivity of 84.6 dB, retinal layers of the human eye in-vivo can be resolved during optical coherence tomography (OCT) examination. The developed FDML laser enables acquisition rates of 3D-volumes with a size of 200 × 100 × 256 voxels in under 100 milliseconds. Detailed information on the FDML implementation, its challenging design tasks, and OCT images obtained with the laser are presented in this paper.
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