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Transplantation of adipose-derived mesenchymal stem cell sheets directly into the kidney suppresses the progression of renal injury in a diabetic nephropathy rat model.

Shunsuke TakemuraTatsuya ShimizuMasatoshi OkaSachiko SekiyaTetsuya Babazono
Published in: Journal of diabetes investigation (2019)
Transplantation of ASC sheets directly into the kidney improved transplantation efficiency and suppressed renal injury progression. Therefore, the ASC sheet technology might be a promising novel treatment for DN.
Keyphrases
  • diabetic nephropathy
  • cell therapy
  • mesenchymal stem cells
  • nlrp inflammasome
  • signaling pathway
  • stem cells
  • umbilical cord