Specific Targeting of Mesothelin-Expressing Malignant Cells Using Nanobody-Functionalized Magneto-Fluorescent Nanoassemblies.

Tina BriolayJudith FresquetDamien MeyerBrigitte KerfelecPatrick ChamesEléna IshowChristophe Blanquart

Published in: International journal of nanomedicine (2024)

Altogether, these results open the path to novel anticancer strategies based on MSLN-activated internalization of NA incorporating drugs to promote specific accumulation of active treatments in tumors.

Keyphrases

quantum dots
induced apoptosis
cell cycle arrest
minimally invasive
cancer therapy
endoplasmic reticulum stress
oxidative stress
signaling pathway
drug delivery
label free
high resolution
single molecule
liquid chromatography