Hemostatic imbalance induced by tamoxifen in estrogen receptor-positive breast cancer patients: An observational study.

Marie DidembourgSara RedaJohannes OldenburgHeiko RühlJonathan DouxfilsLaure Morimont

Published in: International journal of laboratory hematology (2024)

This observational study showed that patients in remission from ER+ breast cancer taking tamoxifen had altered thrombin generation, as well as an acquired APC resistance. Moreover, this is the first study using the validated ETP-based APC resistance assay in tamoxifen-treated patients.

Keyphrases

estrogen receptor
end stage renal disease
positive breast cancer
newly diagnosed
ejection fraction
prognostic factors
peritoneal dialysis
systemic lupus erythematosus
breast cancer cells
single cell