Systemic interindividual epigenetic variation in humans is associated with transposable elements and under strong genetic control.

Chathura J GunasekaraHarry MacKayC Anthony ScottShaobo LiEleonora LaritskyMaria S BakerSandra L GrimmGoo JunYumei LiRui ChenJoseph L WiemelsCristian CoarfaRobert A Waterland

Published in: Genome biology (2023)

A focus on systemic interindividual epigenetic variants, clearly enhanced in mQTL content, should likewise benefit studies attempting to link human epigenetic variation to the risk of disease.

Keyphrases

dna methylation
gene expression
copy number
endothelial cells
genome wide
induced pluripotent stem cells