Acute acetate administration increases endogenous opioid levels in the human brain: A [11C]carfentanil molecular imaging study.
Abhishekh Hulegar AshokJim MyersGary FrostSamuel TurtonRoger N GunnJan PasschierAlessandro ColasantiTiago Reis MarquesDavid NuttAnne Lingford-HughesOliver D HowesEugenii A RabinerPublished in: Journal of psychopharmacology (Oxford, England) (2021)
We have demonstrated that an acute acetate challenge has the potential to increase EO release in the human brain, providing a plausible mechanism of the central effects of acetate on appetite in humans.