Reduced expression of the P-glycoprotein gene PxABCB1 is linked to resistance to Bacillus thuringiensis Cry1Ac toxin in Plutella xylostella (L.).

Junlei ZhouZhaojiang GuoShi KangJianying QinLijun GongDan SunLe GuoLiuhong ZhuYang BaiZhuzhu ZhangXiaomao ZhouYou-Jun Zhang

Published in: Pest management science (2019)

Our results demonstrated that down-regulation of the PxABCB1 gene is associated with both laboratory-selected and field-evolved Cry1Ac resistance in P. xylostella. This knowledge will be conducive to further elucidating the complicated molecular basis of Bt resistance and developing new insect resistance management tactics. © 2019 Society of Chemical Industry.

Keyphrases

escherichia coli
genome wide
copy number
gene expression
zika virus