Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification.
Robert L HollisAlison M MeynertCaroline O MichieTzyvia RyeMichael ChurchmanAmelia Hallas-PottsIan CroyW Glenn McCluggageAlistair R W WilliamsClare BartosYasushi IidaAikou OkamotoBrian DoughertyJ Carl BarrettRuth MarchAthena MatakidouPatricia RoxburghColin A SempleD Paul HarkinRichard KennedyC. Simon HerringtonCharlie GourleyPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
These data paint a high-resolution picture of the molecular landscape in HGSOC, better defining patients who may benefit most from specific molecular therapeutics and highlighting those for whom novel treatment strategies are needed to improve outcomes.