Use of Intracytoplasmic Sperm Injection and Birth Outcomes in Women Conceiving through In Vitro Fertilization.
Xu XiongRichard P DickeyPierre BuekensJeffrey G ShafferGabriella PridjianPublished in: Paediatric and perinatal epidemiology (2017)
Higher rates of birth defects were observed among women conceiving through ICSI. Since approximately half of all ICSI procedures are performed in couples without male factor infertility, ICSI may be overused in practice.