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COVID-19 in congenital heart disease (COaCHeD) study.

Sian Catherine ChiversAoife ClearyRachel KnowlesSonya V Babu-NarayanJohn M SimpsonHeba NashatKonstantinos DimopoulosMichael A GatzoulisDirk WilsonMilos PricaJames AnthonyPaul F CliftVictoria JowettPetra JenkinsBernadette KhodaghalianCaroline B JonesAntonia HardimanCatherine HeadOwen MillerNatali Ay ChungUmar MahmoodFrances A Bu'LockTristan K W RamcharanAshish ChikermaneJennifer ShortlandAndrew TometzkiDavid Steven CrosslandZdenka ReinhardtClive LewisLeila RitteyDominic HaresOlga PanagiotopoulouBenjamin SmithMuhammad Najih LTara BharuchaPiers Ef Daubeney
Published in: Open heart (2023)
Children were at low risk of death and hospitalisation secondary to COVID-19 even with severe CHD, but hospital admission rates were higher in younger children, independent of comorbidity. In adults, higher likelihood of death was associated with increasing age and PAH, and of hospitalisation with age, comorbidities and genetic disease. An individualised approach, based on age and comorbidities, should be taken to COVID-19 management in patients with CHD.
Keyphrases
  • coronavirus disease
  • sars cov
  • congenital heart disease
  • young adults
  • emergency department
  • healthcare
  • respiratory syndrome coronavirus
  • early onset
  • gene expression
  • drug induced