[The burden of progression of psoriatic arthritis. All-Russian register data].
Y L KorsakovaE I LoginovaTatiana V KorotaevaE E GubarSvetlana GlukhovaE A VasilenkoEvgeniy NasonovPublished in: Terapevticheskii arkhiv (2022)
In patients with PsA duration 36 mo we found significant prevalence of erosions by X-Ray, axial PsA, BMI30 kg/m2, HAQ-DI1, PsAID-124, arterial hypertension, metabolic syndrome and overall comorbidity (p0.05). There were no significant differences between groups in PsO severity by BSA3%, PASI1, LEI1, TJC, SJC, dactylitis, ESR30 mm/h, CRP10 mg/l, DAPSA, diabetes mellitus, hyperlipidemia, coronary heart disease and liver damage (p0.05). Сonclusion. Long-standing stage PsA is associated with erosions, axial PsA, worst health related quality of life, functional disability and increased cardio-metabolic disorders and overall comorbidity. Our results support the idea to start bDMARDs at early stage of PsA, it can improve better outcomes.
Keyphrases
- prostate cancer
- radical prostatectomy
- early stage
- metabolic syndrome
- arterial hypertension
- risk factors
- body mass index
- oxidative stress
- high resolution
- insulin resistance
- electronic health record
- magnetic resonance imaging
- mass spectrometry
- skeletal muscle
- sentinel lymph node
- lymph node
- contrast enhanced
- artificial intelligence