Risk of cardiovascular involvement in pediatric patients with X-linked hypophosphatemia.

Olaya Hernández-FríasHelena Gil-PeñaJosé M Pérez-RoldánSusana González-SanchezGema AricetaSara ChocrónReyner LozaFrancisco de la Cerda OjedaLeire MadariagaInés VergaraMarta Fernández-FernándezSusana Ferrando-MonleónMontserrat Antón-GameroÁngeles Fernández-MasedaM Isabel Luis-YanesFernando Santos Rodríguez

Published in: Pediatric nephrology (Berlin, Germany) (2019)

XLH pediatric patients receiving conventional treatment have echocardiographic measurements of ventricular mass within normal reference values, but above the mean, and 18% have LVMI suggestive of left ventricular hypertrophy without correlation with serum FGF23 concentrations. This might indicate an increased risk of cardiovascular involvement in XLH.

Keyphrases

left ventricular
heart failure
mitral valve
left atrial
hypertrophic cardiomyopathy
cardiac resynchronization therapy
acute myocardial infarction
aortic stenosis
coronary artery disease
combination therapy
replacement therapy
young adults
smoking cessation
percutaneous coronary intervention
ejection fraction