Methylation-derived inflammatory measures and lung cancer risk and survival.
Naisi ZhaoMengyuan RuanDevin C KoestlerJiayun LuLucas A SalasKarl T KelseyElizabeth A PlatzDominique S MichaudPublished in: Clinical epigenetics (2021)
Our study demonstrates that immunity status measured with DNA methylation markers is associated with lung cancer a decade or more prior to cancer diagnosis. A better understanding of immunity-associated methylation-based biomarkers in lung cancer development could provide insight into critical pathways.