Expert guidance on the management and challenges of long-COVID syndrome: a systematic review.
Josuel OraLuigino CalzettaChiara FrugoniErmanno PuxedduRogliani PaolaPublished in: Expert opinion on pharmacotherapy (2023)
'Long-COVID' syndrome is a new emergency characterized by several symptoms such as fatigue, dyspnea, cognitive and attention disorders, sleep disorders, post-traumatic stress disorder, muscle pain, and concentration problems. Despite the many guidelines available to date, there are no established treatments of long-COVID. Pharmacological research is studying known drugs that act on the reduction or modulation of systemic inflammation, or innovative drugs used in similar pathologies. Rehabilitation now seems to be the safest treatment to offer, whereas we will have to wait for the pharmacological research trials in progress as well as plan new trials based on a better understanding of the pathogenic mechanisms.
Keyphrases
- coronavirus disease
- sars cov
- sleep quality
- mental health
- chronic pain
- case report
- emergency department
- clinical practice
- public health
- healthcare
- respiratory syndrome coronavirus
- physical activity
- skeletal muscle
- working memory
- pain management
- neuropathic pain
- spinal cord injury
- depressive symptoms
- drug induced
- combination therapy
- emergency medical