Hepatitis D virus infection, innate immune response and antiviral treatments in stem cell-derived hepatocytes.

Frauke LangeJonathan GarnHolda A AnaghoFlorian W R VondranThomas von HahnThomas PietschmannArnaud Carpentier

Published in: Liver international : official journal of the International Association for the Study of the Liver (2023)

The HDV in vitro mono-infection model represents a new tool to study HDV replication, its host-pathogen interactions and evaluate new antiviral drugs in cells displaying mature hepatic functions.

Keyphrases

innate immune
stem cells
induced apoptosis
cell cycle arrest
candida albicans
endoplasmic reticulum stress
cell proliferation
mesenchymal stem cells