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Ozonolysis of α-angelica lactone: a renewable route to malonates.

Andrea Dell'AcquaLukas WilleBernhard M StadlerSergey TinJohannes G de Vries
Published in: Chemical communications (Cambridge, England) (2021)
Industrially relevant intermediates such as malonic acid, malonates and 3-oxopropionates can be easily accessed by ozonolysis of α-angelica lactone, derived from the platform chemical levulinic acid. The roles of the solvent and of the quenching conditions are of key importance for the outcome of the reaction.
Keyphrases
  • high throughput
  • single cell
  • quantum dots