Associations between the von Willebrand Factor-ADAMTS13 Axis, Complement Activation, and COVID-19 Severity and Mortality.

György SinkovitsMarienn RétiVeronika MüllerZsolt IványiJános GálLászló GopcsaPéter ReményiBeáta SzathmáryBotond LakatosJános SzlávikIlona BobekZita Z ProhászkaZsolt FörhéczBlanka MezőDorottya Csuka Lisa HurlerErika KajdácsiLászló CervenakPetra KiszelTamás MassziIstván Vályi-NagyZoltán Prohászka

Published in: Thrombosis and haemostasis (2022)

Our results suggest that an interaction between the VWF-ADAMTS13 axis and complement overactivation and consumption plays an important role in the pathogenesis of COVID-19.

Keyphrases

coronavirus disease
sars cov
cardiovascular events
respiratory syndrome coronavirus
risk factors
coronary artery disease