APOE and spatial navigation in amnestic MCI: results from a computer-based test.

Jan LaczóRoss Andel Martin VyhnálekKamil VlcekZuzana NedelskaVaclav MatoskaIvana GazovaIvana MokrisovaKaterina SheardovaJakub Hort

Published in: Neuropsychology (2014)

Using an easy-to-use, computer-based tool to assess spatial navigation, we found spatial navigation deficits to worsen in a dose-dependent manner as a function of APOE ε4 status. This was at least partially due to differences in right hippocampal volume.

Keyphrases

mild cognitive impairment
cognitive decline
deep learning
high fat diet
traumatic brain injury
adipose tissue
skeletal muscle
blood brain barrier