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Dominant immune response to HLA-B57/B58 molecules after platelet transfusion.

Justine CoombsLatifa Ben HassenMathieu LeclercMarie TamagneLouise PannetierMehdi KhelfaAdèle DelormeThibaut BocquetSébastien MauryFrançoise PirenneHélène Ansart-PirenneBenoît Vingert
Published in: Transfusion (2020)
These results shed light on posttransfusion class I anti-HLA alloimmunization mechanisms and constitute a first step toward developing new strategies for reducing refractoriness.
Keyphrases
  • immune response
  • sickle cell disease
  • cardiac surgery
  • dendritic cells
  • toll like receptor