Monitoring Unfractionated Heparin in Adult Patients Undergoing Extracorporeal Membrane Oxygenation (ECMO): ACT, APTT, or ANTI-XA?

Tung Phi NguyenXuan Thi PhanDai Quang HuynhHa Thi Viet TruongYen Nguyen Hai LeTuan Manh NguyenQuan Quoc Minh DuThao Phuong LeHai Ngoc TruongThi Thi HoThao Thi Ngoc Pham

Published in: Critical care research and practice (2021)

APTT value is strongly correlated with anti-Xa value, particularly in patients with normal antithrombin levels. However, the ACT value was poorly correlated with anti-Xa and not with the UFH dose. In groups without antithrombin deficiency, APTT and anti-Xa values only moderately correlated with UFH dose.

Keyphrases

extracorporeal membrane oxygenation
acute respiratory distress syndrome
patients undergoing
respiratory failure
intensive care unit
replacement therapy
smoking cessation