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Tracing back of relapse clones by Ig/TCR gene rearrangements reveals complex patterns of recurrence in pediatric acute lymphoblastic leukemia.

Ming-Zhu JiaWei-Jing LiChan-Juan WangQing ZhangChao GaoXiao-Tong HuangTing ZhuRui-Dong ZhangLei CuiZhi-Gang Li
Published in: International journal of laboratory hematology (2023)
Backtracking Ig/TCR gene rearrangements in relapse clones of pediatric ALL revealed complex patterns of clonal selection and evolution for leukemic relapse.
Keyphrases
  • free survival
  • acute lymphoblastic leukemia
  • regulatory t cells
  • genome wide
  • copy number
  • genome wide identification
  • acute myeloid leukemia
  • allogeneic hematopoietic stem cell transplantation
  • single cell