Graft-versus-host disease in patients with bone marrow transplants: A retrospective study analyzing outcomes and healthcare burden in US hospitals.
Rushin PatelAfoma OnyechiJessica Ohemeng-DapaahMrunal PatelDarshil PatelZalak PatelYu-Han ChenChieh YangPublished in: European journal of haematology (2024)
GVHD in individuals undergoing BMT is linked to elevated mortality rates, prolonged hospitalization, and higher healthcare costs. Moreover, they face a significantly increased risk of developing complications, such as sepsis, pneumonia, acute respiratory failure, C. difficile infection, and AKI. These results underscore the critical need for vigilant monitoring and effective GVHD management to improve patient outcomes and reduce the complications associated with BMT. Nevertheless, further prospective studies are essential to obtain a more profound understanding and a comprehensive assessment of outcomes in these hospitalized patients.
Keyphrases
- respiratory failure
- healthcare
- extracorporeal membrane oxygenation
- bone marrow
- risk factors
- mechanical ventilation
- acute kidney injury
- allogeneic hematopoietic stem cell transplantation
- intensive care unit
- liver failure
- cardiovascular events
- intellectual disability
- cardiovascular disease
- adipose tissue
- skeletal muscle
- case control
- community acquired pneumonia