Anti-HNA testing of allo-exposed COVID-19 convalescent plasma donors including genetic human neutrophil antigen screening to prevent anti-HNA antibody-mediated transfusion-related acute lung injury.

Katarzyna GuzPatrycja ŁopaczMałgorzata UhrynowskaKarolina PiaskowskaBeata SzczepaniakMagdalena KrzemienowskaSylwia Purchla-SzepiołaAnna GłówkaEliza Głodkowska-MrówkaAgnieszka Orzińska

Published in: Transfusion (2024)

Due to applying HNA genotyping as a primary test before anti-HNA antibody testing the serological work was limited only to HNA-homozygous donors revealing two anti-HNA immunized donors. The distribution of HNA genotypes in the cohort was similar to other Caucasian populations.

Keyphrases

coronavirus disease
genome wide
sars cov
kidney transplantation
gene expression
high throughput
lps induced
copy number
induced pluripotent stem cells
respiratory syndrome coronavirus