Results from London Regional Clinical Genetics services over a 5-year period on germline TP53 testing in women diagnosed with breast cancer at <30 years.

Alice GarrettSabrina TalukdarLouise IzattAngela F BradySinead WhyteKatherine S JosephsMonisha ShanmugasundaramLi Shan GuillemotDara VakiliShevaun EyMunaza Ahmed

Published in: Journal of medical genetics (2021)

Germline TP53 PVs/LPVs are uncommon among women diagnosed with breast cancer aged <30 years without other relevant personal or family cancer history but have an important clinical impact when identified.

Keyphrases

breast cancer risk
polycystic ovary syndrome
dna repair
pregnancy outcomes
healthcare
papillary thyroid
cervical cancer screening
primary care
mental health
squamous cell
type diabetes
adipose tissue
young adults
skeletal muscle
lymph node metastasis