Inactivation of SARS-CoV-2 infectivity in platelet concentrates or plasma following treatment with ultraviolet C light or with methylene blue combined with visible light.
Jody Hobson-PetersAlberto A AmarillaLina RustantiDenese C MarksEileen V RoulisAlexander A KhromykhNaphak ModhiranDaniel WattersonStefan ReichenbergFrank TolksdorfChryslain SumianAxel SeltsamUte GravemannHelen M FaddyPublished in: Transfusion (2022)
SARS-CoV-2 infectivity was reduced in plasma and platelets following treatment with the THERAFLEX MB-Plasma and THERAFLEX UV-Platelets systems, to the limit of detection, respectively. These PI technologies could therefore be an effective option to reduce the risk of transfusion-transmitted emerging pathogens.