CircRNA inhibits DNA damage repair by interacting with host gene.

Xiaolong XuJingwei ZhangYihao TianYang GaoXin DongWenbo ChenXiaoning YuanWeinan YinJinjing XuKe ChenChunjiang HeLei Wei

Published in: Molecular cancer (2020)

Our results revealed a new regulatory mechanism for circRNA on its host gene and provided evidence that circSMARCA5 may serve as a therapeutic target for drug-resistant breast cancer patients.

Keyphrases

drug resistant
dna damage
multidrug resistant
acinetobacter baumannii
copy number
genome wide
oxidative stress
transcription factor
dna repair
single cell
gene expression
dna methylation
protein kinase
cystic fibrosis
genome wide analysis