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DNA hypermethylation of NOTCH2NLC in neuronal intranuclear inclusion disease: a case-control study.

Yuwen CaoWotu TianJingying WuXingwang SongZhaoxia WangXinghua Luan
Published in: Journal of neurology (2022)
Our findings suggested the aberrant DNAm status of the NOTCH2NLC promoter in NIID, and we explored the link between DNAm levels and disease features quantitatively for the first time, which may help to further explore pathogenic mechanism.
Keyphrases
  • cell proliferation
  • dna methylation
  • gene expression
  • transcription factor
  • single molecule
  • circulating tumor
  • cerebral ischemia