Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice.
David L GoldblattJose R FloresGabriella Valverde HaAna M JaramilloSofya TkachmanCarson T KirkpatrickShradha WaliBelinda HernandezDavid E OstBrenton L ScottJichao ChenScott E EvansMichael J TuvimBurton F DickeyPublished in: British journal of pharmacology (2020)
These data suggest that treatment of susceptible human hosts with aerosolized ODN and Pam2 at the time of a respiratory viral infection might attenuate the severity of the acute infection and reduce initiation, exacerbation and progression of asthma.
Keyphrases
- chronic obstructive pulmonary disease
- liver failure
- respiratory failure
- drug induced
- lung function
- endothelial cells
- aortic dissection
- hepatitis b virus
- big data
- type diabetes
- high fat diet induced
- mouse model
- combination therapy
- machine learning
- insulin resistance
- replacement therapy
- respiratory tract
- smoking cessation