Mapping hippocampal and thalamic atrophy in epilepsy: A 7-T magnetic resonance imaging study.
Alfredo LucasSofia MouchtarisAshley TranquilleNishant SinhaRyan GallagherMarissa MojenaJoel M SteinSandhitsu DasKathryn A DavisPublished in: Epilepsia (2024)
Leveraging 7-T MRI, we demonstrate widespread hippocampal and thalamic atrophy in epilepsy. Through unsupervised machine learning, we demonstrate patterns of volumetric atrophy that vary depending on disease subtype. Incorporating these atrophy patterns into clinical practice could help better stratify patients to surgical treatments and specific device implantation strategies.
Keyphrases
- magnetic resonance imaging
- machine learning
- end stage renal disease
- clinical practice
- ejection fraction
- deep brain stimulation
- temporal lobe epilepsy
- newly diagnosed
- contrast enhanced
- chronic kidney disease
- computed tomography
- prognostic factors
- peritoneal dialysis
- deep learning
- artificial intelligence
- diffusion weighted imaging
- big data
- patient reported outcomes
- magnetic resonance
- high density
- brain injury
- patient reported