A prospective investigation of interleukin-8 levels in pediatric acute respiratory failure and acute respiratory distress syndrome.
Heidi FloriAnil SapruMichael W QuasneyGinny GildengorinMartha A Q CurleyMichael A MatthayMary K Dahmernull nullPublished in: Critical care (London, England) (2019)
When measured sequentially, plasma IL-8 was robustly associated with multiple, relevant clinical outcomes including mortality, but was not associated with PARDS development. The wide range of plasma IL-8 levels exhibited in this cohort suggests that further study into the heterogeneity of this patient population and its impact on individual responses to PARDS treatment is warranted.