Ketamine versus ECT for Nonpsychotic Treatment-Resistant Major Depression.
Amit AnandSanjay J MathewGerard SanacoraJames W MurroughFernando S GoesMurat AltinayAmy S AloysiAli A Asghar-AliBrian S BarnettLee C ChangKatherine A CollinsSara CostiSidra IqbalManish K JhaKamini KrishnanDonald A MaloneSina NikayinSteven E NissenRobert B OstroffIrving M RetiSamuel T WilkinsonKathy WolskiBo HuPublished in: The New England journal of medicine (2023)
Ketamine was noninferior to ECT as therapy for treatment-resistant major depression without psychosis. (Funded by the Patient-Centered Outcomes Research Institute; ELEKT-D ClinicalTrials.gov number, NCT03113968.).