Association Analysis of Essential Tremor-Associated Genetic Variants in Sporadic Late-Onset Parkinson's Disease.

Sheng Zeng Xun Zhou Runcheng He Yuwen Zhao Zheng-Hua Liu Qian Xu Ji-Feng Guo Xinxiang Yan Jinchen Li Bei-Sha Tang Qiying Sun

Published in: Tremor and other hyperkinetic movements (New York, N.Y.) (2024)

1962 cases and 1279 controls were recruited to study the potential genetic interplay between ET-associated genetic loci/variants and sporadic LOPD.No significant association between the ET-associated SNPs and LOPD were observed.No significant burden of rare deleterious variants of ET-associated gene in LOPD risk were found.

Keyphrases

late onset
genome wide
copy number
early onset
dna methylation
deep brain stimulation
gene expression
risk assessment
genome wide identification
genome wide association study