Robustness of dual-energy CT-derived radiomic features across three different scanner types.

• Inter-scanner robustness of dual-energy CT-derived radiomic features was on a low level in patients who underwent clinical examinations on three DECT platforms. • The few robust patient-derived features were not confirmed in our phantom experiment. • Limited inter-scanner robustness of dual-energy CT derived radiomic features may impact the generalizability of models built with features from one particular dual-energy CT scanner type.