Clinical phenotypes of adults with monogenic and syndromic genetic obesity.

Mila S WellingMostafa MohseniRenate E H MeeusenCornelis J de Groot Mariëtte R Boon Lotte Kleinendorst Jenny A Visser Mieke M van Haelst Erica L T van den Akker Elisabeth F C van Rossum

Published in: Obesity (Silver Spring, Md.) (2024)

We found distinct phenotypes in adult genetic obesity. Additionally, we demonstrated low sensitivity for detecting genetic obesity in adults using pediatric ES recommendations, necessitating specific genetic testing recommendations in adult obesity care.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
genome wide
healthcare
palliative care
adipose tissue
skeletal muscle
clinical practice
intellectual disability
gene expression
autism spectrum disorder
young adults
pain management