Serine O-acetyltransferase derived NV14 peptide reduces cytotoxicity in H 2 O 2 induced MDCK cells and inhibits MCF-7 cell proliferation through caspase gene expression.

Manikandan Velayutham Balasubramanian HaridevamuthuP Snega PriyaMunuswamy Ramanujam GaneshAnnie JulietJesu Arockia Raj

Published in: Molecular biology reports (2022)

Together, this study demonstrates that NV14 has a potent antioxidant and anti-cancer capability; however, further direction needs to be focused on clinical or pharmacodynamics aspects.

Keyphrases

induced apoptosis
gene expression
cell proliferation
oxidative stress
cell cycle arrest
cell death
diabetic rats
dna methylation
high glucose
signaling pathway
cell cycle
drug induced
endothelial cells
protein kinase