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Transcriptionally imprinted glycomic signatures of acute myeloid leukemia.

Constantin BlöchlDi WangOleg A MayborodaGuinevere S M Lageveen-KammeijerDana L E Vergoossen
Published in: Cell & bioscience (2023)
Taken together, our data suggest transcriptionally imprinted glycomic signatures of AML, reflecting their differentiation status and FAB classification. This study expands our insights into the emerging field of AML glycosylation and paves the way for studies of FAB class-associated glycan repertoires of AML blasts and their functional implications.
Keyphrases
  • acute myeloid leukemia
  • allogeneic hematopoietic stem cell transplantation
  • genome wide
  • machine learning
  • deep learning
  • electronic health record
  • big data
  • solid phase extraction
  • high resolution
  • data analysis