Markers of acute kidney injury in patients with sepsis: the role of soluble thrombomodulin.

Shinshu KatayamaShin NunomiyaKansuke KoyamaMasahiko WadaToshitaka KoinumaYuya GotoKen TonaiJun Shima

Published in: Critical care (London, England) (2017)

Endothelial biomarkers were significantly changed in the sepsis patients with AKI. Particularly, sTM was an independent predictive biomarker for the development of AKI that outperformed other coagulation and inflammation biomarkers as well as organ function in patients with sepsis.

Keyphrases

acute kidney injury
septic shock
intensive care unit
oxidative stress
endothelial cells