Do patients with type 2 diabetes mellitus included in randomised clinical trials differ from general-practice patients? A cross-sectional comparative study.
Amandine DugardBruno GiraudeauClarisse Dibao-DinaPublished in: BMJ open (2024)
Patients with type 2 diabetes mellitus cared for in general practice differ in a number of important aspects from patients included in randomised controlled trials on which clinical practice guidelines are based. This situation hampers the applicability of these guidelines. Future randomised trials should include patients who better fit the 'average' general-practice patient with type 2 diabetes mellitus to help improve the translation of study findings in daily practice.
Keyphrases
- general practice
- end stage renal disease
- clinical trial
- ejection fraction
- chronic kidney disease
- newly diagnosed
- primary care
- peritoneal dialysis
- prognostic factors
- open label
- cardiovascular disease
- adipose tissue
- study protocol
- patient reported outcomes
- weight loss
- case report
- clinical practice
- cardiovascular risk factors