Luteolin as potential treatment for Huntington's disease: Insights from a transgenic mouse model.

Abuelnor Mohammed Azza Ramadan Ayah Moath Alkherat Ali Awadallah Ali Mohamed Saeed Nadia Al Mazrouei Fahad T Alsulami Yousef Saeed Alqarni Vineetha Bharathan Menon Abdulla Al Amoodi Sami Fatehi Abdalla

Published in: CNS neuroscience & therapeutics (2024)

Luteolin holds promise as a therapeutic agent for improving survival outcomes, managing motor dysfunction, and reducing huntingtin aggregates in HD. The findings are of significance as currently, there are no approved therapeutic interventions that reverse HD pathology or slow down its progression.

Keyphrases

mouse model
physical activity
oxidative stress
machine learning
replacement therapy
deep learning
smoking cessation
artificial intelligence