SIRPB1 promotes prostate cancer cell proliferation via Akt activation.

Qiong SongSiyuan QinLaura E PascalChunlin ZouWenchu WangHaibo TongJian ZhangWilliam J CatalonaRajiv DhirMegan MorrellGoundappa K BalasubramaniYi LuZhou Wang

Published in: The Prostate (2020)

These results suggest that SIRPB1 is a potential oncogene capable of activating Akt signaling to stimulate prostate cancer proliferation and could be a biomarker for patients at risk of developing aggressive prostate cancer.

Keyphrases

prostate cancer
cell proliferation
signaling pathway
radical prostatectomy
cell cycle
risk assessment