Abscopal Effect Following Immunotherapy and Combined Stereotactic Body Radiation Therapy in Recurrent Metastatic Head and Neck Squamous Cell Carcinoma: A Report of Two Cases and Literature Review.
Jonathan S ChoiEugene R SansoniBenjamin D LovinNathan R LindquistJack PhanLauren L MayoRenata FerrarottoShirley Y SuPublished in: The Annals of otology, rhinology, and laryngology (2019)
Observation of abscopal effect with combined IT and RT is currently under investigation through several preclinical studies and trials. To the best of our knowledge, these are the first two reported cases of abscopal effect for patients with HNSCC. We report two patients with R/M HNSCC with sustained, complete response after systemic IT and local RT.