Updated Percentiles for the University of Pennsylvania Smell Identification Test in Adults 50 Years of Age and Older.

Updated age/sex-specific UPSIT percentiles are provided for ≥50-year-old adults who reflect a population likely to be recruited into studies of prodromal neurodegenerative diseases. Our findings highlight the potential advantages of evaluating olfaction relative to age and sex instead of in absolute terms (e.g., based on raw UPSIT scores) or based on subjective (i.e., self-reported) measures. This information addresses the need to support studies of disorders including PD and Alzheimer's disease by providing updated normative data from a larger sample of older adults.