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Simultaneous Quantification of Methotrexate and Its Metabolite 7-Hydroxy-Methotrexate in Human Plasma for Therapeutic Drug Monitoring.

Xinxin RenZhipeng WangYunlei YunGuangyi MengXialan ZhangHuamin DingYing XuHansheng BaiJing LiuXia LiShou-Hong GaoLifeng HuangWan-Sheng Chen
Published in: International journal of analytical chemistry (2019)
The method was successfully developed and applied to the routine therapeutic drug monitoring of MTX and 7-OH-MTX in human plasma.
Keyphrases
  • high dose
  • clinical practice