PD-L1 expression in ROS1-rearranged non-small cell lung cancer: A study using simultaneous genotypic screening of EGFR, ALK, and ROS1.

Jongmin LeeChan Kwon ParkHyoung-Kyu YoonYoung Jo SaIn Sook WooHyo Rim KimSue Youn KimTae-Jung Kim

Published in: Thoracic cancer (2018)

In the largest consecutive routine Asian NSCLC cohort analyzed to date, we found that high PD-L1 expression frequently overlapped with ROS1 rearrangement, while it negatively correlated with EGFR mutations.

Keyphrases

small cell lung cancer
cell death
dna damage
reactive oxygen species
epidermal growth factor receptor
advanced non small cell lung cancer
tyrosine kinase
brain metastases